{"id":263,"date":"2011-02-23T04:25:10","date_gmt":"2011-02-23T04:25:10","guid":{"rendered":"http:\/\/www.wi.rwth-aachen.de\/SmartMedCN\/?p=263"},"modified":"2011-02-23T04:25:10","modified_gmt":"2011-02-23T04:25:10","slug":"lacking-volunteer-in-children-drug-clinical-tests","status":"publish","type":"post","link":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/2011\/02\/23\/lacking-volunteer-in-children-drug-clinical-tests\/","title":{"rendered":"Lacking Volunteer in Children Drug Clinical Tests"},"content":{"rendered":"

2011-02-23<\/strong><\/em><\/span><\/p>\n

A dilemma in the children drug R&D : the demands of children drugs are rapidly increasing. However, it’s extremely difficult to have clinical tests for new children drugs, because most parents won’t let their children test new drugs. Researchers are calling for more support from the public. <\/strong><\/p>\n

 <\/p>\n

\n\u805a\u7126\u201c\u836f\u7269\u5371\u673a\u201d\uff1a\u4e2d\u56fd\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7f3a\u4e4f<\/h3>\n

 <\/p>\n

\u6587\u7ae0\u6765\u6e90\uff1a\u65b0\u534e\u7f51<\/p>\n

\u76d1\u6d4b\u8868\u660e\uff0c\u4e2d\u56fd\u513f\u7ae5\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u7387\u662f\u6210\u4eba\u76842\u500d\uff0c\u65b0\u751f\u513f\u66f4\u662f\u8fbe\u52304\u500d\uff0c\u4e2d\u56fd\u6bcf\u5e74\u6b7b\u4e8e\u4e0d\u826f\u7528\u836f\u8005\u76841\/3\u90fd\u662f\u513f\u7ae5<\/p>\n

\u4e2d\u56fd\u513f\u7ae5\u7ea6\u5360\u603b\u4eba\u53e3\u6570\u768420%\uff0c\u4f46\u5c5e\u4e8e\u4ed6\u4eec\u7684\u836f\u7269\u53ea\u5360\u603b\u836f\u54c1\u6570\u76842%\u3002<\/p>\n

\u5728\u201c\u65e0\u836f\u53ef\u7528\u201d\u7684\u73b0\u5b9e\u4e0b\uff0c\u7279\u522b\u662f\u2161\u578b\u7cd6\u5c3f\u75c5\u3001\u6291\u90c1\u75c7\u7b49\u75be\u75c5\u5728\u513f\u7ae5\u4e2d\u7684\u53d1\u75c5\u7387\u65e5\u8d8b\u8d70\u9ad8\u7684\u80cc\u666f\u4e0b\uff0c\u513f\u7ae5\u4e0d\u5f97\u4e0d\u5c06\u9488\u5bf9\u6210\u4eba\u7684\u836f\u7269\uff0c\u7f29\u51cf\u836f\u91cf\u52a0\u4ee5\u670d\u7528\u3002<\/p>\n

\u533b\u5b66\u8bc1\u636e\u663e\u793a\uff0c\u513f\u7ae5\u548c\u6210\u5e74\u4eba\u5bf9\u836f\u7269\u7684\u53cd\u5e94\u5dee\u5f02\u5f88\u5927\uff0c\u4e00\u79cd\u5bf9\u6210\u5e74\u4eba\u6709\u6548\u7684\u836f\u7269\u4e5f\u8bb8\u5e76\u4e0d\u9002\u7528\u4e8e\u513f\u7ae5\uff0c\u540c\u6837\u7684\u5dee\u522b\u751a\u81f3\u5b58\u5728\u4e8e\u4e0d\u540c\u5e74\u9f84\u3001\u4f53\u91cd\u548c\u8eab\u4f53\u72b6\u51b5\u7684\u513f\u7ae5\u4e4b\u95f4\u3002<\/p>\n

\u7531\u4e8e\u8fd9\u4e9b\u836f\u7269\u7684\u4f9d\u636e\u6765\u81ea\u6210\u4eba\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u800c\u513f\u7ae5\u4e0e\u836f\u7269\u4ee3\u8c22\u3001\u89e3\u6bd2\u529f\u80fd\u5bc6\u5207\u76f8\u5173\u7684\u810f\u5668\uff0c\u5982\u809d\u3001\u80be\u7b49\u90fd\u5728\u751f\u957f\u53d1\u80b2\u4e2d\uff0c\u8ddf\u6210\u4eba\u6709\u8f83\u5927\u5dee\u5f02\uff0c\u6545\u5f88\u53ef\u80fd\u53d1\u751f\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n

\u76d1\u6d4b\u8868\u660e\uff0c\u4e2d\u56fd\u513f\u7ae5\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u7387\u662f\u6210\u4eba\u76842\u500d\uff0c\u65b0\u751f\u513f\u66f4\u662f\u8fbe\u52304\u500d\uff0c\u4e2d\u56fd\u6bcf\u5e74\u6b7b\u4e8e\u4e0d\u826f\u7528\u836f\u8005\u76841\/3\u90fd\u662f\u513f\u7ae5\u3002<\/p>\n

\u6362\u8a00\u4e4b\uff0c\u8fd9\u4e9b\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u5728\u6210\u4eba\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u65e0\u6cd5\u9884\u77e5\u3001\u540e\u679c\u96be\u6599\u3002\u60e8\u75db\u7684\u6559\u8bad\u5305\u62ec\u6c99\u5229\u5ea6\u80fa\u81f4\u201c\u6d77\u8c79\u80a2\u7578\u5f62\u201d\u5a74\u513f\u3001\u6c2f\u9709\u7d20\u81f4\u201c\u7070\u5a74\u7efc\u5408\u5f81\u201d\u7b49\uff0c\u5176\u4ed6\u8bf8\u5982\u6251\u5c14\u654f\u6613\u81f4\u513f\u7ae5\u70e6\u8e81\u3001\u65b0\u9709\u7d20\u6ef4\u8033\u5242\u53ef\u81f4\u5a74\u513f\u542c\u529b\u53d7\u635f\u3001\u6ef4\u9f3b\u51c0\u53ef\u5f15\u53d1\u5c0f\u513f\u4e2d\u6bd2\u7b49\uff0c\u4e5f\u90fd\u8ba9\u5bb6\u5ead\u548c\u793e\u4f1a\u4ed8\u51fa\u96be\u4ee5\u8ba1\u91cf\u7684\u4ee3\u4ef7\u3002<\/p>\n

\u9664\u201c\u65e0\u836f\u53ef\u7528\u201d\u5916\uff0c\u201c\u7528\u836f\u4e0d\u5f53\u201d\u4e5f\u6b63\u4e0d\u65ad\u66b4\u9732\u5f0a\u7aef\u201c\u4e09\u7d20\u4e00\u6c64\u201d(\u6297\u751f\u7d20\u3001\u6fc0\u7d20\u3001\u7ef4\u751f\u7d20\u548c\u8f93\u6db2)\u6ee5\u7528\u5bfc\u81f4\u7684\u836f\u6e90\u6027\u75be\u75c5\u6b63\u4e0d\u65ad\u593a\u8d70\u513f\u7ae5\u7684\u5065\u5eb7\u3002<\/p>\n

\u663e\u7136\uff0c\u4e2d\u56fd\u513f\u7ae5\u6b63\u9762\u4e34\u4e00\u573a\u201c\u836f\u7269\u5371\u673a\u201d\u3002<\/p>\n

\u5bf9\u6b64\uff0c\u4e2d\u56fd\u513f\u7ae5\u536b\u751f\u4fdd\u5065\u75be\u75c5\u9632\u6cbb\u6307\u5bfc\u4e2d\u5fc3\u4e3b\u4efb\u3001\u4e16\u754c\u536b\u751f\u7ec4\u7ec7(WHO)\u513f\u7ae5\u536b\u751f\u5408\u4f5c\u4e2d\u5fc3\u4e3b\u4efb\u6234\u8000\u534e\u544a\u8bc9\u300a\u77ad\u671b\u300b\u65b0\u95fb\u5468\u520a\uff1a\u201c\u4e2d\u56fd\u513f\u7ae5\u836f\u7269\u7684\u73b0\u72b6\u9700\u8981\u5c3d\u5feb\u6539\u89c2\uff0c\u653f\u5e9c\u3001\u4f01\u4e1a\u3001\u516c\u4f17\u5e94\u5f53\u643a\u624b\uff0c\u4e3a\u513f\u7ae5\u91cf\u8eab\u5b9a\u5236\u836f\u7269\u3002\u201d<\/p>\n

\u836f\u7269\u77ed\u7f3a<\/p>\n

\u636e\u6234\u8000\u534e\u4ecb\u7ecd\uff0c\u5728\u76ee\u524d3000\u591a\u79cd\u836f\u7269\u4e2d\uff0c\u513f\u7ae5\u836f\u7269\u5927\u81f4\u670960\u79cd\uff0c\u4f46\u5373\u4fbf\u662f\u8fd960\u79cd\u836f\u7269\uff0c\u4e5f\u5b58\u5728\u5242\u578b\u5355\u4e00\u3001\u54c1\u79cd\u5355\u8c03\u7684\u95ee\u9898\u3002<\/p>\n

\u5728 \u5979\u770b\u6765\uff0c\u513f\u7ae5\u836f\u7269\u7684\u5242\u578b\u5e94\u8be5\u662f\u6bd4\u8f83\u597d\u670d\u7528\u7684\uff0c\u6bd4\u5982\u51b2\u5242\u3001\u53e3\u670d\u6db2\uff0c\u4f46\u8fd93000\u591a\u79cd\u836f\u7269\u4e2d\uff0c\u5f88\u591a\u662f\u7247\u5242\uff0c\u751a\u81f3\u662f\u80f6\u56ca\uff0c\u4e14\u4e0d\u8bf4\u5b83\u7684\u6709\u6548\u6027\u3001\u526f\u4f5c\u7528\uff0c\u5355\u5355\u670d\u7528\uff0c \u5bf93\u5c81\u4ee5\u4e0b\u5a74\u5e7c\u513f\u5c31\u662f\u4e2a\u96be\u9898\u3002\u201c\u836f\u7247\u8fd8\u597d\u5206\uff0c\u80f6\u56ca\u600e\u4e48\u5206\uff1f\u80f6\u56ca\u672c\u8eab\u5c31\u4e0d\u5b9c\u5206\u5272\uff0c\u5b83\u5c31\u662f\u5e0c\u671b\u5403\u8fdb\u53bb\u5bf9\u80c3\u80a0\u9053\u523a\u6fc0\u5c0f\u4e00\u70b9\uff0c\u90a3\u73b0\u5728\u53ea\u80fd\u662f\u628a\u80f6\u56ca\u836f\u7269\u6253\u5f00\u3001\u5206\u597d\uff0c \u518d\u4e70\u80f6\u56ca\u58f3\u6765\u88c5\uff0c\u8fd9\u5f88\u9ebb\u70e6\u3002\u201d<\/p>\n

\u6b64\u5916\uff0c\u6210\u4eba\u836f\u7269\u5f80\u5f80\u836f\u7247\u6bd4\u8f83\u5927\uff0c\u513f\u7ae5\u4e0d\u6613\u541e\u670d\uff0c\u6216\u8005\u672a\u52a0\u77eb\u5473\u54c1\uff0c\u5473\u9053\u6bd4\u8f83\u82e6\uff0c\u513f\u7ae5\u5f88\u96be\u63a5\u53d7\u3002<\/p>\n

\u53e6\u4ece\u513f\u7ae5\u836f\u7269\u54c1\u79cd\u6765\u770b\uff0c\u6b62\u54b3\u3001\u5065\u80c3\u3001\u52a9\u6d88\u5316\u7b49\u5e38\u89c4\u836f\u5c45\u591a\uff0c\u5fc3\u810f\u75c5\u3001\u809d\u75c5\u3001\u80be\u75c5\u7b49\u7684\u513f\u7ae5\u836f\u7269\u8fd8\u6bd4\u8f83\u7f3a\u4e4f\u3002<\/p>\n

\u201c\u636e\u6211\u4e86\u89e3\uff0c\u4e00\u4e9b\u4f01\u4e1a\u4e0d\u662f\u4e0d\u613f\u610f\u7814\u53d1\u513f\u7ae5\u836f\u7269\uff0c\u5ba1\u6279\u7a0b\u5e8f\u590d\u6742\u7684\u786e\u5f88\u8ba9\u4ed6\u4eec\u70e6\u607c\u3002\u201d\u6234\u8000\u534e\u8868\u793a\u3002<\/p>\n

\u5979 \u4e3e\u4f8b\u8bf4\uff0c\u513f\u7ae5\u62c9\u809a\u5b50\u8131\u6c34\u5f88\u5e38\u89c1\uff0c\u7279\u522b\u662f\u75c5\u6bd2\u6027\u79cb\u5b63\u8179\u6cfb\uff0c\u6ca1\u6709\u7279\u6548\u836f\uff0c\u76ee\u524d\u591a\u91c7\u7528\u8f93\u6db2\u6cbb\u7597\u3002\u4f46\u65e9\u57282004\u5e74\uff0cWHO\u548c\u8054\u5408\u56fd\u513f\u7ae5\u57fa\u91d1\u4f1a\u5c31\u53d1\u8868\u8fc7\u8054\u5408\u58f0\u660e\uff0c \u63a8\u8350\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u8179\u6cfb\u7684\u65b0\u578b\u4f4e\u6e17\u900f\u6027\u53e3\u670d\u8865\u6db2\u76d0(ORS)\u548c\u8865\u950c\u5242\uff0c\u8ba4\u4e3aORS\u52a0\u950c\u53ef\u4ee5\u7f29\u77ed\u75c5\u7a0b\u3001\u51cf\u8f7b\u75c5\u60c5\u3002\u201c\u6709\u4f01\u4e1a\u544a\u8bc9\u6211\u4ed6\u4eec\u6253\u7b97\u5c06ORS\u548c\u950c\u6df7\u5408\uff0c\u5236 \u6210\u4e00\u79cd\u65b0\u836f\uff0c\u6211\u8bf4\u8fd9\u662f\u5927\u597d\u4e8b\u5440\uff0c\u4ec0\u4e48\u65f6\u5019\u80fd\u4e0a\u5e02\uff1f\u4ed6\u4eec\u8bf4\u9884\u8ba1\u5ba1\u6279\u8981\u82b13\u5e74\u3002\u6211\u5c31\u4e0d\u660e\u767d\u4e86\uff0cORS\u6ca1\u95ee\u9898\uff0c\u950c\u4e5f\u6ca1\u95ee\u9898\uff0c\u628a\u5b83\u4eec\u6df7\u5408\u8d77\u6765\u600e\u4e48\u5c31\u9700\u8981\u75283\u5e74\u7684\u65f6 \u95f4\u6765\u5ba1\u6279\uff1f\u8fd9\u4e2a\u836f\u7684\u9700\u6c42\u91cf\u90a3\u4e48\u5927\uff0c\u6700\u5173\u952e\u7684\u662f\uff0c\u60a3\u513f\u6709\u8fd9\u4e2a\u836f\u5c31\u4e0d\u7528\u53bb\u8f93\u6db2\u4e86\uff0c\u8fd9\u4e0d\u662f\u80fd\u5927\u5927\u51cf\u5c11\u8fc7\u5ea6\u8f93\u6db2\u7684\u5371\u5bb3\u5417\uff1f\u201d<\/p>\n

\u4e13\u6ce8\u513f\u7ae5\u7528\u836f\u7684\u5eb7\u829d\u836f\u4e1a\uff0c\u5176\u4e3b\u6253\u4ea7\u54c1\u745e\u829d\u6e05(\u5c3c\u7f8e\u8212\u5229\u9897\u7c92)\u867d\u5728\u8fd1\u671f\u906d\u9047\u8d28\u7591\uff0c\u4f46\u8fd9\u5bb62007\u5e74\u6210\u7acb\u3001\u73b0\u79f0\u201c\u5728\u513f\u7ae5\u7528\u836f\u9886\u57df\u7684\u7814\u53d1\u53ca\u751f\u4ea7\u80fd\u529b\u5df2\u5904\u4e8e\u56fd\u5185\u9886\u5148\u5730\u4f4d\u201d\u7684\u4f01\u4e1a\uff0c\u5176\u5bf9\u513f\u7ae5\u836f\u7269\u7814\u53d1\u7684\u4f53\u4f1a\u4ecd\u9700\u5f15\u8d77\u91cd\u89c6\u3002<\/p>\n

2010 \u5e743\u6708\uff0c\u4e00\u4efd\u540d\u4e3a\u300a\u6d77\u5357\u5eb7\u829d\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f8\u521b\u4e1a\u677f\u9996\u53d1\u62db\u80a1\u8bf4\u660e\u4e66(\u7533\u62a5\u7a3f)\u300b\u7684\u6587\u7ae0\u5199\u9053\uff1a\u201c\u513f\u7ae5\u836f\u7814\u53d1\u751f\u4ea7\u5b58\u5728\u4ee5\u4e0b\u4e09\u4e2a\u65b9\u9762\u7684\u56f0\u96be\uff1a\u4e00\u662f\u65b0\u4ea7\u54c1\u5f00\u53d1\u6295\u5165 \u8f83\u5927\u3001\u5468\u671f\u8f83\u957f\u3002\u513f\u7ae5\u836f\u54c1\u7684\u7814\u7a76\u5f00\u53d1\u9700\u8981\u9ad8\u989d\u6295\u5165\uff0c\u4e14\u5f00\u53d1\u5468\u671f\u8f83\u957f\u3002\u4e8c\u662f\u836f\u7269\u8bc4\u4ef7\u96be\u5ea6\u5927\u3002\u836f\u7269\u4e0a\u5e02\u8981\u7ecf\u8fc7\u4eba\u4f53\u8bd5\u9a8c\uff0c\u4f46\u4f9d\u636e\u56fd\u9645\u4f26\u7406\u51c6\u5219\uff0c\u4e0d\u662f\u6240\u6709\u7684\u836f\u54c1\u90fd \u53ef\u4ee5\u5728\u513f\u7ae5\u8eab\u4e0a\u505a\u8bd5\u9a8c\u3002\u4e09\u662f\u751f\u4ea7\u9500\u552e\u98ce\u9669\u5927\u3002\u4e00\u65b9\u9762\u513f\u7ae5\u836f\u5bf9\u5b89\u5168\u8981\u6c42\u7279\u522b\u9ad8\uff1b\u800c\u53e6\u4e00\u65b9\u9762\uff0c\u513f\u7ae5\u7528\u836f\u5e02\u573a\u672c\u6765\u5e94\u8be5\u662f\u4e00\u4e2a\u5927\u5e02\u573a\uff0c\u4f46\u662f\u7531\u4e8e\u4f20\u7edf\u4e60\u60ef\u7684\u5c40\u9650\uff0c\u4f7f \u6210\u4eba\u836f\u54c1\u6324\u5360\u4e86\u513f\u7ae5\u7528\u836f\u5e02\u573a\uff0c\u5982\u679c\u6ca1\u6709\u4e13\u95e8\u7684\u9500\u552e\u6e20\u9053\uff0c\u901a\u5e38\u7684\u836f\u54c1\u751f\u4ea7\u4f01\u4e1a\u65e0\u6cd5\u53d6\u5f97\u5f88\u597d\u7684\u5e02\u573a\u6548\u76ca\u3002\u201d<\/p>\n

\u5c3d\u7ba1\u5982\u6b64\uff0c\u6234\u8000\u534e\u4ecd\u5f3a\u8c03\u7814\u53d1\u513f\u7ae5\u836f\u7269\u7684\u91cd\u8981\u6027\uff1a\u201c\u5982\u679c\u4e0d\u5f00\u53d1\u513f\u7ae5\u836f\u7269\uff0c\u7279\u522b\u662f\u7f3a\u4e4f\u513f\u7ae5\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u90a3\u5c31\u76f8\u5f53\u4e8e\u8ba9\u6240\u6709\u513f\u7ae5\u53bb\u505a\u8bd5\u9a8c\uff0c\u53bb\u9a8c\u8bc1\u836f\u7269\uff0c\u8fd9\u4e2a\u98ce\u9669\u4e0d\u662f\u66f4\u5927\u5417\uff1f\u201d<\/p>\n

\u5317 \u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u7684\u513f\u79d1\u6559\u6388\u738b\u4e3d\u66fe\u4e3b\u5bfc\u4e2d\u56fd\u9996\u4e2a\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u7814\u7a76\uff0c\u662f\u4e2d\u56fd\u513f\u7ae5\u836f\u7269\u9886\u57df\u7684\u6743\u5a01\u4e13\u5bb6\u4e4b\u4e00\u3002\u5979\u57282009\u5e74\u300a\u513f\u79d1\u836f\u5b66\u6742\u5fd7\u300b\u520a\u53d1\u7684\u300a\u9ad8\u5ea6\u5173\u6ce8\u513f\u7ae5 \u7528\u836f\u7684\u5b89\u5168\u6027\u300b\u4e00\u6587\u4e2d\u79f0\uff1a\u201c\u8fd1\u5e74\u6211\u9662\u513f\u7ae5(1\u5929\uff5e18\u5c81)ADR(\u5373\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u8bb0\u8005\u6ce8)\u53d1\u751f\u7387\u4e3a10.7%\uff1b\u6297\u611f\u67d3\u836f\u536052%\uff0c\u4e2d\u67a2\u795e\u7ecf\u836f\u5360 20.8%\uff0c\u6297\u80bf\u7624\u836f\u53606.49%\uff1b\u76ae\u80a4\u635f\u5bb3\u536064%\uff0c\u5168\u8eab\u6027\u635f\u5bb3\u536011.5%\uff0c\u8868\u73b0\u4e3a\u8fc7\u654f\u6027\u4f11\u514b\u3001\u53d1\u70ed\u3001\u547c\u5438\u56f0\u96be\u3001\u77ed\u65f6\u610f\u8bc6\u4e27\u5931\u7b49\uff1b\u9759\u8109\u7ed9\u836f\u5360 49.9%\uff0c\u53e3\u670d\u7ed9\u836f\u536042.1%\u3002\u201d<\/p>\n

\u201c\u5927\u5bb6\u603b\u8bf4\u513f\u7ae5\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6709\u4f26\u7406\u4e0a\u7684\u5236\u7ea6\u3001\u4e0d\u5bb9\u6613\u62db\u52df\u5fd7\u613f\u8005\u7b49\uff0c\u4f46\u6211\u4eec\u8fd8\u662f\u8981\u591a\u60f3\u529e\u6cd5\u3002\u201d\u6234\u8000\u534e\u8bf4\u3002<\/p>\n

[PAGELIST] \u3000\u3000\u636e\u5979\u4ecb\u7ecd\uff0c\u5979\u66fe\u53c2\u4e0e\u505a\u8fc7\u513f\u7ae5\u751f\u957f\u6fc0\u7d20\u7c7b\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u201c\u5f53\u65f6\u4e5f\u8981\u62db\u52df\u5fd7\u613f\u8005\uff0c\u4f46\u6574\u4e2a\u8fc7\u7a0b\u4e0b\u6765\uff0c\u6211\u89c9\u5f97\u5bb6\u957f\u8fd8\u662f\u6bd4\u8f83\u914d\u5408\uff0c\u5f53\u7136\u4f60\u4e0d\u80fd\u641e\u4e00\u4e9b\u6bd2\u6027\u5927\u7684\uff0c \u90a3\u662f\u7f3a\u5fb7\uff0c\u4f46\u5c31\u662f\u6211\u521a\u8bf4\u7684ORS\u52a0\u950c\u8fd9\u79cd\uff0c\u6211\u8ba4\u4e3a\u8bd5\u9a8c\u5df2\u7ecf\u505a\u5f97\u5f88\u591a\u4e86\uff0c\u5927\u5bb6\u4e5f\u76f8\u5f53\u6709\u628a\u63e1\u4e86\uff0c\u90fd\u77e5\u9053\u4e0d\u4f1a\u6709\u4ec0\u4e48\u95ee\u9898\uff0c\u53ea\u662f\u9700\u8981\u4e34\u5e8a\u9a8c\u8bc1\u800c\u5df2\uff0c\u6211\u89c9\u5f97\u62db\u52df\u5fd7\u613f \u8005\u5e94\u8be5\u4e0d\u7b97\u5f88\u96be\u3002<\/p>\n

\u4e0d\u5f53\u7528\u836f<\/p>\n

\u6234\u8000\u534e\u8bf4\uff0c\u201c\u5927\u5bb6\u4e00\u63d0\u8d77\u80bf\u7624\u7684\u5316\u7597\u90fd\u5f88\u5bb3\u6015\uff0c\u5176\u5b9e\u5316\u5b66\u836f\u54c1\u4e5f\u662f\u4e00\u79cd\u5316\u5b66\u7684\u6cbb\u7597\uff0c\u4e5f\u662f\u4e0d\u80fd\u968f\u610f\u4f7f\u7528\u7684\uff0c\u4f46\u73b0\u5728\uff0c\u5305\u62ec\u8fc7\u5ea6\u8f93\u6db2\u3001\u6297\u751f\u7d20\u6ee5\u7528\u7b49\u5728\u5185\u7684\u7528\u836f\u4e0d\u5f53\u95ee\u9898\uff0c\u5927\u5bb6\u8fd8\u4e0d\u662f\u592a\u91cd\u89c6\u3002\u201d<\/p>\n

2006\u5e74\uff0c\u4e00\u9879\u5bf9158\u5bb6\u4e09\u7532\u533b\u9662\u7684\u8c03\u67e5\u663e\u793a\uff0c\u6297\u751f\u7d20\u4f7f\u7528\u738772.23%\uff0c\u56f4\u624b\u672f\u671f\u4e00\u7c7b\u5207\u53e3\u9884\u9632\u7528\u836f\u8fbe97%\uff0c\u8f93\u6db2\u6bd4\u56fd\u5916\u591a3\u500d\u3002<\/p>\n

\u6234 \u8000\u534e\u8bf4\uff1a\u201c\u6709\u4e9b\u75c5\u6bd4\u5982\u611f\u5192\u3001\u53d1\u70e7\uff0c\u672c\u6765\u6ca1\u4ec0\u4e48\u5371\u9669\uff0c\u4f46\u8f93\u6db2\u53cd\u5e94\u5374\u53ef\u80fd\u5371\u53ca\u751f\u547d\uff0c\u6240\u4ee5\u56fd\u5916\u5f80\u5f80\u628a\u9759\u8109\u8f93\u6db2\u5f53\u4f5c\u4e00\u4ef6\u5f88\u8c28\u614e\u7684\u4e8b\uff0c\u4e0d\u662f\u968f\u4fbf\u5c31\u80fd\u8f93\u6db2\u7684\u3002\u4f60\u518d\u770b\u4e2d \u56fd\u56fd\u5185\uff0c\u540a\u6c34\u8f93\u6db2\u7b80\u76f4\u53f8\u7a7a\u89c1\u60ef\u3002\u6240\u4ee5\u6211\u6709\u65f6\u5019\u89c9\u5f97\u8001\u767e\u59d3\u7684\u8840\u7ba1\u4e5f\u633a\u5389\u5bb3\uff0c\u4ec0\u4e48\u90fd\u80fd\u5f80\u91cc\u88c5\u3002\u800c\u4e14\u8fd9\u8fd8\u4e0d\u5355\u662f\u533b\u751f\u8bda\u4fe1\u7684\u95ee\u9898\uff0c\u6709\u65f6\u5019\u5c31\u662f\u533b\u751f\u7684\u7406\u5ff5\u7684\u95ee\u9898\u3002\u201d<\/p>\n

\u5979 \u89e3\u91ca\u8bf4\uff0c\u6bd4\u5982\uff0c\u611f\u5192\u662f\u75c5\u6bd2\u6027\u7684\uff0c\u7528\u6297\u751f\u7d20\u6ca1\u6548\u679c\uff0c\u4f46\u6709\u7684\u533b\u751f\u4ed6\u81ea\u5df1\u611f\u5192\u4e86\uff0c\u4e5f\u4f1a\u53bb\u7528\u6297\u751f\u7d20\u3001\u4f1a\u53bb\u8f93\u6db2\uff0c\u533b\u751f\u81ea\u5df1\u7684\u8111\u5b50\u91cc\u4e5f\u8ba4\u4e3a\u6297\u751f\u7d20\u3001\u8f93\u6db2\u6709\u6548\uff0c\u4f46\u8fd9\u662f\u6ca1 \u6709\u79d1\u5b66\u4f9d\u636e\u7684\u3002\u201c\u533b\u751f\u90fd\u6ca1\u6709\u8fd9\u4e2a\u4fe1\u5ff5\uff0c\u5bb6\u957f\u5927\u6982\u66f4\u4f1a\u8ff7\u4fe1\u8f93\u6db2\u3001\u6297\u751f\u7d20\uff0c\u4e8e\u662f\u518d\u5411\u533b\u751f\u63d0\u8981\u6c42\uff0c\u8fc7\u5ea6\u8f93\u6db2\u3001\u6ee5\u7528\u6297\u751f\u7d20\u7684\u95ee\u9898\u81ea\u7136\u6108\u6f14\u6108\u70c8\u3002\u201d<\/p>\n

\u6234 \u8000\u534e\u66fe\u53bb\u519c\u6751\u4e61\u9547\u536b\u751f\u9662\u505a\u201c\u513f\u7ae5\u75be\u75c5\u7efc\u5408\u7ba1\u7406\u201d\u7684\u57f9\u8bad\u3002\u5979\u7684\u7ecf\u9a8c\u662f\uff0c\u73b0\u5728\u533b\u60a3\u5173\u7cfb\u6bd4\u8f83\u7d27\u5f20\uff0c\u5373\u4fbf\u5df2\u7ecf\u786e\u5b9a\u662f\u75c5\u6bd2\u6027\u611f\u67d3\uff0c\u4f46\u4e00\u4e9b\u533b\u751f\u6ca1\u6709\u628a\u63e1\uff0c\u4e5f\u4f1a\u91c7\u53d6\u9632\u536b \u6027\u7528\u836f\u3001\u9884\u9632\u6027\u7528\u836f\u7684\u7b56\u7565\uff0c\u7ed9\u60a3\u513f\u5f00\u6297\u751f\u7d20\u3002\u201c\u6211\u4eec\u5c31\u5f97\u6559\u4ed6\u7528\u6570\u547c\u5438\u6b21\u6570\u7684\u529e\u6cd5\u53bb\u5224\u65ad\u5230\u5e95\u662f\u4e0d\u662f\u80ba\u708e\uff0c\u5982\u679c\u572830\u5de6\u53f3\u5c31\u80fd\u628a\u63e1\u4e0d\u662f\u80ba\u708e\uff0c\u90a3\u5c31\u4e0d\u8981\u5f00\u6297\u751f \u7d20\uff0c\u5982\u679c\u533b\u751f\u8fd8\u662f\u62c5\u5fc3\uff0c\u6211\u4eec\u5c31\u6559\u4ed6\u5728\u533b\u5631\u91cc\u5199\u660e\uff0c\u73b0\u5728\u8ba4\u4e3a\u662f\u54b3\u55fd\u3001\u611f\u5192\uff0c\u6ca1\u6709\u80ba\u708e\uff0c\u4f46\u5982\u679c\u5b69\u5b50\u51fa\u73b0\u547c\u5438\u6025\u4fc3\u3001\u4e0d\u597d\u597d\u5403\u4e1c\u897f\u3001\u8001\u60f3\u7761\u89c9\u7b49\u75c7\u72b6\uff0c\u8bf7\u9a6c\u4e0a\u56de\u6765\u590d \u8bca\uff0c\u8fd9\u6837\u4e00\u6765\uff0c\u5373\u4fbf\u4e3e\u8bc1\u8d23\u4efb\u5012\u7f6e\u4e5f\u53ef\u4ee5\u51cf\u8f7b\u533b\u751f\u7684\u8d23\u4efb\u3002\u201d<\/p>\n

\u6234\u8000\u534e\u8bf4\uff0c\u4ed6\u4eec\u505a\u8fd9\u4e2a\u57f9\u8bad\u4e0d\u4e45\uff0c\u5c31\u6709\u4e61\u9547\u536b\u751f\u9662\u7684\u9662\u957f\u8ddf\u5979\u8bb2\u533b\u9662\u7684\u6536\u5165\u964d\u4f4e\u4e86\uff0c\u56e0\u4e3a\u6ca1\u6709\u8fc7\u5ea6\u7528\u836f\u4e86\u3002\u201c\u4f46\u8fd9\u5bf9\u8001\u767e\u59d3\u786e\u5b9e\u662f\u6709\u5229\u7684\u5440\uff0c\u6211\u5e38\u5e38\u60f3\uff0c\u8fd9\u4e9b\u95ee\u9898\u8981\u662f\u90fd\u80fd\u771f\u6b63\u89e3\u51b3\u4e86\uff0c\u513f\u7ae5\u770b\u75c5\u96be\u3001\u770b\u75c5\u8d35\u7684\u77db\u76fe\u4e5f\u5c31\u4e0d\u5b58\u5728\u4e86\u3002\u201d<\/p>\n

\u8bf4 \u8d77\u7528\u836f\u4e0d\u5f53\uff0c\u6234\u8000\u534e\u8bf4\uff0c\u6709\u4e9b\u5b69\u5b50\u4e00\u62c9\u809a\u5b50\u3001\u4e00\u54b3\u55fd\u3001\u4e00\u611f\u5192\uff0c\u533b\u751f\u9a6c\u4e0a\u5c31\u4e0a\u4e09\u4ee3\u5934\u5b62\uff0c\u201c\u8fd9\u5728\u56fd\u5916\u662f\u4e0d\u53ef\u80fd\u7684\u3002\u6fb3\u5927\u5229\u4e9a\u7684\u533b\u751f\u8ddf\u6211\u8bf4\uff0c\u4ed6\u4eec\u90a3\u91cc\u660e\u786e\u89c4\u5b9a\u4ec0\u4e48\u836f \u7531\u4ec0\u4e48\u7ea7\u522b\u7684\u533b\u751f\u5f00\uff0c\u5404\u7ea7\u522b\u533b\u751f\u90fd\u6709\u76f8\u5e94\u7684\u5904\u65b9\u9650\u5236\u6743\uff0c\u6bd4\u5982\u4e09\u4ee3\u5934\u5b62\u4e0d\u662f\u4e3b\u4efb\u533b\u5e08\u90a3\u662f\u4e0d\u80fd\u5f00\u7684\u3002\u6211\u4eec\u8fd9\u91cc\u7684\u60c5\u51b5\u5219\u662f\uff0c\u53ea\u8981\u6709\u836f\uff0c\u4f4f\u9662\u533b\u3001\u4e61\u9547\u533b\u751f\u90fd\u6709\u5904\u65b9 \u6743\u3002\u201d<\/p>\n

\u738b\u4e3d\u5728\u524d\u8ff0\u6587\u7ae0\u4e2d\u5199\u9053\uff1a\u201c\u76ee\u524d\u513f\u7ae5\u611f\u5192\u836f\u5e94\u7528\u662f\u8fc7\u5ea6\u7684\u3002\u611f\u5192\u53ef\u4ee5\u81ea\u6108\uff0c\u5e02\u573a\u4e0a\u54c1\u724c\u611f\u5192\u836f(\u5982\u65b0\u5eb7\u6cf0\u514b\u7b49)\u90fd\u53ea\u662f\u7f13\u89e3\u75c7\u72b6\u3002\u56fd\u5916\u533b\u751f\u662f\u4e0d\u8f7b\u6613\u7ed9\u75c5\u4eba\u5f00\u611f\u5192\u836f\u7684\uff0c\u4f11\u606f\u591a\u559d\u6c34\u5c31\u662f\u6cbb\u7597\u3002\u201d<\/p>\n

\u56fd\u9645\u516c\u8ba4\uff0c\u6ee5\u7528\u6fc0\u7d20\u662f\u80a1\u9aa8\u5934\u574f\u6b7b\u7684\u5934\u53f7\u6740\u624b\uff0c\u4f46\u5728\u4e00\u4e9b\u57fa\u5c42\u533b\u9662\uff0c\u6fc0\u7d20\u6ee5\u7528\u7684\u60c5\u51b5\u4ecd\u6bd4\u8f83\u4e25\u91cd\uff0c\u8fd9\u5f88\u53ef\u80fd\u5bfc\u81f4\u513f\u7ae5\u53d1\u80b2\u8fdf\u7f13\u3001\u9aa8\u8d28\u758f\u677e\u3001\u514d\u75ab\u529f\u80fd\u4e0b\u964d\u7b49\u3002<\/p>\n

\u6b64\u5916\uff0c\u4e2d\u56fd\u513f\u7ae5\u8fc7\u91cf\u670d\u7528\u7ef4\u751f\u7d20\u5f15\u8d77\u7684\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u4e5f\u9700\u8981\u8b66\u60d5\u3002\u5982\u7ef4\u751f\u7d20A\u8fc7\u91cf\u53ef\u81f4\u538c\u98df\u3001\u5455\u5410\u7b49\uff0c\u7ef4\u751f\u7d20D\u8fc7\u91cf\u53ef\u5f15\u8d77\u8179\u6cfb\u3001\u80be\u810f\u635f\u5bb3\u7b49\uff0c\u7ef4\u751f\u7d20C\u8fc7\u91cf\u53ef\u5f15\u8d77\u8179\u75db\u3001\u8179\u6cfb\u7b49\u3002<\/p>\n

\u201c\u836f\u7269\u5371\u673a\u201d\u80cc\u540e<\/p>\n

\u201c\u65e0\u836f\u53ef\u7528\u201d\u3001\u201c\u7528\u836f\u4e0d\u5f53\u201d\u7684\u80cc\u540e\uff0c\u9690\u85cf\u7740\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7f3a\u4e4f\u8fd9\u4e00\u68d8\u624b\u96be\u9898\u3002<\/p>\n

\u4e3a\u907f\u514d\u513f\u7ae5\u53c2\u4e0e\u4e34\u5e8a\u8bd5\u9a8c\u7684\u98ce\u9669\uff0c\u5728\u6d89\u53ca\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u65f6\uff0c\u533b\u5b66\u4f26\u7406\u89c4\u8303\u6027\u6587\u4ef6\u4e00\u822c\u4f1a\u8981\u6c42\u513f\u7ae5\u4e34\u5e8a\u8bd5\u9a8c\u5fc5\u987b\u83b7\u5f97\u513f\u7ae5\u53d7\u8bd5\u8005\u6cd5\u5b9a\u76d1\u62a4\u4eba\u7b7e\u7f72\u7684\u77e5\u60c5\u540c\u610f\u4e66\u7b49\u3002\u4f46\u4ece\u5168\u7403\u6765\u770b\uff0c\u80af\u8ba9\u5b69\u5b50\u53bb\u505a\u201c\u5c0f\u767d\u9f20\u201d\u7684\u5bb6\u957f\u51e4\u6bdb\u9e9f\u89d2\u3002<\/p>\n

\u8fd9\u53c8\u5e26\u6765\u65b0\u7684\u98ce\u9669\u7f3a\u5c11\u513f\u7ae5\u7fa4\u4f53\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5f88\u96be\u771f\u6b63\u83b7\u5f97\u5b89\u5168\u6709\u6548\u7684\u513f\u7ae5\u836f\u7269\u3002<\/p>\n

\u8fd9\u4e2a\u77db\u76fe\u6b63\u5728\u5f15\u8d77\u5404\u56fd\u653f\u5e9c\u7684\u91cd\u89c6\u3002<\/p>\n

\u8d44 \u6599\u663e\u793a\uff0c\u7f8e\u56fd\u81ea1994\u5e74\u8981\u6c42\u6240\u6709\u65b0\u836f\u7533\u8bf7\u8bf4\u660e\u4e66\u5fc5\u987b\u63d0\u4f9b\u513f\u7ae5\u7528\u836f\u4fe1\u606f\u540e\uff0c1998\u5e74\u5236\u5b9a\u201c\u513f\u79d1\u4f18\u5148\u201d\u76ee\u5f55\uff0c\u5c06\u6bcf\u5e74\u5904\u65b9\u91cf\u8f83\u5927\u7684\u836f\u7269\u5217\u5165\u76ee\u5f55\u5e76\u89c4\u5b9a\u5fc5\u987b\u5728 \u5176\u8bf4\u660e\u4e66\u4e2d\u589e\u52a0\u513f\u7ae5\u7528\u836f\u4fe1\u606f\u3002\u4e3a\u9f13\u52b1\u5236\u836f\u516c\u53f8\u8fdb\u884c\u513f\u79d1\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u7f8e\u56fd\u786e\u5b9a\u5bf9\u836f\u54c1\u8bf4\u660e\u4e66\u63d0\u4f9b\u513f\u79d1\u7528\u836f\u4fe1\u606f\u7684\u4ea7\u54c1\u7ed9\u4e886\u4e2a\u6708\u7684\u4e13\u5229\u5ef6\u957f\u671f\u3002<\/p>\n

2007 \u5e74\uff0c\u6b27\u76df\u5b9e\u65bd\u65b0\u7684\u300a\u513f\u79d1\u836f\u54c1\u7ba1\u7406\u89c4\u7ae0\u300b\uff0c\u5176\u6838\u5fc3\u5185\u5bb9\u4e4b\u4e00\u5c31\u662f\u5728\u6cd5\u5f8b\u6846\u67b6\u5185\u5f15\u5165\u836f\u54c1\u201c\u513f\u79d1\u7814\u7a76\u8ba1\u5212\u201d(PIP)\uff0c\u786e\u4fdd\u7528\u4e8e\u513f\u7ae5\u7684\u836f\u54c1\u7814\u7a76\u5de5\u4f5c\u6210\u4e3a\u836f\u54c1\u7814\u53d1\u4e0d \u53ef\u7f3a\u5c11\u7684\u7ec4\u6210\u90e8\u5206\uff0c\u5e76\u5c06\u5176\u6574\u5408\u81f3\u6210\u4eba\u836f\u54c1\u7814\u53d1\u8ba1\u5212\u4e2d\u3002\u6b64\u5916\uff0c\u5176\u8fd8\u89c4\u5b9a\u81ea2008\u5e747\u670826\u65e5\u8d77\uff0c\u7533\u8bf7\u65b0\u836f\u5fc5\u987b\u63d0\u4ea4PIP\uff0c\u81ea2009\u5e741\u670826\u65e5\u8d77\uff0c\u7533\u8bf7 \u65b0\u9002\u5e94\u75c7\u4e5f\u5fc5\u987b\u63d0\u4ea4PIP\u3002<\/p>\n

\u65e5\u672c\u539a\u751f\u7701\u533b\u836f\u5b89\u5168\u5c40\u4e8e2000\u5e7412\u6708\u9881\u5e03\u300a\u513f\u7ae5\u836f\u54c1\u4e34\u5e8a\u8bd5\u9a8c\u6307\u5357\u300b\uff0c\u5e76\u5b9e\u884c\u5ef6\u957f\u836f\u54c1\u590d\u5ba1\u5e74\u9650\u7684\u653f\u7b56\u4ee5\u9f13\u52b1\u5236\u836f\u4f01\u4e1a\u4ece\u4e8b\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\u4e2d \u56fd\u7684\u513f\u79d1\u836f\u7406\u57fa\u5730\u5efa\u8bbe\u59cb\u4e8e\u4e0a\u4e16\u7eaa80\u5e74\u4ee3\u3002\u636e\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d1\u5e03\u7684\u516c\u544a\uff0c\u622a\u81f32009\u5e747\u670814\u65e5\uff0c\u83b7\u5f97\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u8d44\u683c\u8ba4\u5b9a\u7684\u513f\u79d1\u4e13\u4e1a\u589e\u52a0\u5230 46\u4e2a\uff0c\u4f46\u4ecd\u4ec5\u5360\u83b7\u5f97\u8d44\u683c\u8ba4\u5b9a\u4e13\u4e1a\u6570\u76842.4%\u3002\u540c\u65f6\uff0c\u5404\u4e13\u4e1a\u7684\u6570\u91cf\u5206\u5e03\u4e5f\u4e0d\u5e73\u8861\uff1a\u4e2d\u533b\u513f\u79d116\u4e2a\uff0c\u5c0f\u513f\u547c\u5438\u4e13\u4e1a9\u4e2a\uff0c\u5c0f\u513f\u80be\u75c5\u3001\u5185\u5206\u6ccc\u3001\u795e\u7ecf\u75c5\u5b66\u3001\u611f\u67d3 \u4e13\u4e1a\u54043\u4e2a\uff0c\u5c0f\u513f\u6d88\u5316\u3001\u5fc3\u810f\u75c5\u4e13\u4e1a\u54042\u4e2a\uff0c\u5c0f\u513f\u8840\u6db2\u75c5\u3001\u76ae\u80a4\u3001\u80bf\u7624\u3001\u9057\u4f20\u4ee3\u8c22\u3001\u666e\u901a\u5916\u79d1\u4e13\u4e1a\u54041\u4e2a\u3002<\/p>\n

\u6b64\u79cd\u60c5\u51b5\u663e\u7136\u96be\u4ee5\u6ee1\u8db3\u513f\u7ae5\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7684\u9700\u8981\u3002(\u672c\u6587\u5f97\u5230\u300a\u513f\u79d1\u836f\u5b66\u6742\u5fd7\u300b\u6881\u9896\u6587\u5148\u751f\u7684\u5e2e\u52a9) \u4f5c\u8005\uff1a\u5f20\u5189\u71c3<\/p>\n","protected":false},"excerpt":{"rendered":"

2011-02-23 A dilemma in the children drug R&D : the demands of children drugs are rapidly increasing. However, it’s extremely difficult to have clinical tests for new children drugs, because […]<\/p>\n","protected":false},"author":951,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"c2c_always_allow_admin_comments":false,"footnotes":""},"categories":[5],"tags":[13,23],"class_list":["post-263","post","type-post","status-publish","format-standard","hentry","category-pharmaceutical-company-news","tag-drug-saftey","tag-medication"],"_links":{"self":[{"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/posts\/263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/users\/951"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/comments?post=263"}],"version-history":[{"count":0,"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/posts\/263\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/media?parent=263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/categories?post=263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.rwth-aachen.de\/smartmedcn\/wp-json\/wp\/v2\/tags?post=263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}